Molecular Formula | C12H16N2O |
Molar Mass | 204.27 |
Density | 1.0565 (rough estimate) |
Melting Point | 137-139oC |
Boling Point | 342.77°C (rough estimate) |
Specific Rotation(α) | 30D -224° (c = 1.05 in water) |
Flash Point | 191.9°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Vapor Presure | 1.24E-06mmHg at 25°C |
Appearance | White crystalline powder |
Color | White to Off-White |
pKa | 9.61±0.20(Predicted) |
Storage Condition | -20°C Freezer, Under Inert Atmosphere |
Refractive Index | 1.6000 (estimate) |
MDL | MFCD00211091 |
Physical and Chemical Properties | White Crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from the dry root of Sophora flavescens, Needle Leaf Huang Hua. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
WGK Germany | 3 |
RTECS | HA4400000 |
Toxicity | LD50 in mice (mg/kg): 21 i.v.; 51 i.p. (Barlow, McLeod) |
Plant source: | Sophora flavescens |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
biological activity | N-Methylcytisine (Caulophylline) is a tricyclic quinoline alkaloid with hypoglycemic, analgesic and anti-inflammatory activities. N-Methylcytisine is a selective ligand for acetylcholine nicotinic receptors in the central nervous system and has a high affinity (Kd: 50 nM) for nicotinic acetylcholine receptors in the squid optic ganglion. |
target | kd: 50 nM (nicotinic acetylcholine receptors) |
uses | N-methylnodipine has anti-arrhythmia, anti-microbial infection, anti-ulcer and anti-cancer effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effect: The effect is similar to that of broom and weak. |